With the recent infomine for the original sin, I've relisten to the evilious chronicles playlist.
We don't know Maria face's for now or what actually happenned to her. But we know that somehow, she has a connection to Seth and that she's in a state that would horrify other characters. We also know that she "gave birth" to twins Adam and Eve. And that the MA project was asked to be done in order to "give bodies" to Levia and Behemoth following a "prophetie" that Maria made, it is implied that she might not say the whole truth in Queen of Glass and that she made Adam.
So here's what I think. I think the current Alice Merry-go-around worked with Seth in order to develop the Ghoul children and that she's the one singning Full moon Laboratory. The result of her own research gave her Adam and Even, thus why she had a virginal fecondation. I also think Maria Moonlit is an HER, maybe because of Seth, maybe because she considers Levia and Behemoth her parents, and somehow might have infected her. Also, maybe, they can only communicate mentally with those who have been infected (even if they are cured) with the HER sydrome..Why I think she's an HER? Well, I think either she succeded to make Adam and Even and impregnate herself during Full moon Laboratory or she tried again later but hurted herself so bad she was no longer a fonctionnal being. The thing is that, she clearly kill or hurt stuff during Full moon Laboratory.
Whatever the reason, she couldn't fonction properly. I think she's probably a corpse in the white house in the labyrinth of glass or a shell horribly wounded. Whatever the case, we'll see with punishment. But I think think she's conscious anymore.
And I think Seth transfered her soul into the ghoul child Irina. I don't know if HER can be soul transfered, but I think Seth didn't want Irina to have all of Maria's memories and would serve as an experiment based on her past desires. Also it would make sence if they discovered how to make inheritors during the time Maria was working with Seth in the laboratory to perfect the Goul children formula. Thus explaining why Eve would have been an Inheritor in the first place. Why not make Adam the same? I don't know. Would the processus have impact with Eve psychy? Maybe.
So yeah, what do you think?