Board Thread:General Discussion/@comment-6192846-20160505033846/@comment-26928472-20160522082245

Most Romance languages (Spanish, French, Italian, Catalan, Portuguese, etc.) use the same word for both sadness and pain (e.g. dolor, dolore, douleur) while Portuguese uses different words: "Tristeza" for sadness/sorrow and "dor" for pain. The same happens in Latin: Tristitia and dolor. Depression and despair are separate things, too.

If you want to be literal, I think sadness/sorrow would be the best option. But interpreting it some more, maybe depression or melancholy could fit. I prefer sorrow anyway.